Madikwe Game Reserve is one of the few reserves in southern Africa, which is malaria free. Located in South Africa along the Botswana border and 20 kilometres from Gaberone, the reserve lies within a transition region between Lowveld bushveld and the Kalahari thornveld. As a result the region is host to an incredible diversity of species from both ecosystems.

Geographically the region has enormous volcanic intrusions known as Inselbergs, wide open plains and the riverine environment along the Marico River in the east of the reserve.

Thakadu River Camp is a wholly-owned, Community-based Tented Safari Camp within Madikwe Game Reserve. The Camp, on the banks of the Marico River, is an ecotourism partnership between North-West Parks, the Molatedi Community and The Madikwe Collection.

The community has a 45-year lease to operate a commercial lodge with traversing rights across the Reserve. The concept is unique in South Africa in that the community owns the development, with substantial benefits accruing to the community itself.